Trust AI has unveiled Isaac PracticeOS, a practice management system built entirely on artificial intelligence. The product will launch at the 2026 Chicago Dental Society Midwinter Meeting in Chicago.
According to the company, Isaac PracticeOS is designed to move beyond data storage and actively interpret and act on clinical, operational, and financial information within a dental practice. When a treatment plan is created, the system prepares the insurance claim with the correct codes, verified coverage, and a clinical narrative. If a patient cancels, the platform identifies a replacement from the waitlist and contacts the patient before the appointment time goes unused. Dentists can query production metrics in plain language and receive responses in seconds. An AI receptionist responds to after-hours patient calls based on appointment history, balance, and insurance status.
At the foundation of the system is Isaac OneHealth, which the company describes as one of only two AIs in history to score a perfect 100% on the USMLE medical boards. According to the company, that clinical intelligence is available free to dentists and powers modules within PracticeOS, including treatment planning and insurance narratives.
Isaac PracticeOS consolidates billing, clinical charting, imaging, treatment planning, insurance verification, scheduling, patient communications, e-prescribing, and practice analytics into a single platform. Thirteen integrated modules share the same data and patient record. Plans start at $299 per month. According to the company, many practices currently rely on multiple systems that together cost between $1,500 and $2,000 per month.
“Every dentist I talk to tells me the same thing: they spend their day managing software instead of managing care,” said Dr. Bernard Casse, CEO and co-founder of Trust AI. “They’re paying for eight, nine, ten different tools, and none of them talk to each other. They’re losing money to denied claims they didn’t have time to prepare properly. They’re losing patients to schedule gaps nobody saw coming. And the worst part is, most of them don't even know how much it's costing them because no single tool gives them the full picture. We built Isaac to be the one system that handles all of it, so the dentist can go back to being a dentist.”
The company was co-founded by clinicians who, according to the company, experienced limitations with existing dental technology.
“I’ve practiced dentistry for years, and the technology we rely on has barely changed,” said Dr. Divian Patel, chief clinical officer and co-founder of Trust AI, a partner at San Ramon Dental Excellence. “As clinicians, we know what we need: a system that thinks the way we think. Isaac understands treatment sequences, insurance nuances, and patient history at a level that no traditional PMS has ever attempted. This is what dentists have been asking for. We just had to build it ourselves.”
“AI is separating practices into two categories: those operating on memory and those operating on intelligence,” said Dr. Shervin Molayem, chief innovation officer and co-founder of Trust AI, a periodontist based in Los Angeles. “We frequently see dentists catch coverage gaps and surface clinical considerations that would otherwise be missed. That is intelligence embedded directly into the clinical workflow, improving with every use.”
More than 8,000 dentists have joined the Trust AI platform, according to the company. The company raised $6.5 million in what it described as the largest seed round for a dental technology startup, with most of the funding coming from dentists who use the product.
Live demonstrations of Isaac PracticeOS are scheduled during the Midwinter Meeting at Booth 5023 in the West Building, Hall F.
Trust AI, based in Silicon Valley, develops artificial intelligence systems for dental practices. More information is available at trustdentistry.ai.
